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Paroxetine is known as a selective serotonin reuptake inhibitorSSRIThis medication may improve your moodsleepappetiteand energy level and may help restore your interest in daily livingIt may decrease fearanxietyunwanted thoughtsand the number of panic attacksParoxetine may lessen premenstrual symptoms such as irritabilityincreased appetiteand depression.

Excreted in breast milkuse cautionAAP states effect on nursing infants is unknown but may be of concern)

Concomitant use or within 14 days of MAOIs increases risk of serotonin syndrome Reactions to concomitant administration with MAOIs include tremormyoclonusdiaphoresisnauseavomitingflushingdizzinesshyperthermia with features resembling neuroleptic malignant syndromeseizuresrigidityautonomic instability with possible rapid fluctuations of vital signsand mental status changes that include extreme agitation progressing to delirium and coma Starting paroxetine in a patient who is being treated with linezolid or IV methylene blue is contraindicated because of an increased risk of serotonin syndrome If linezolid or IV methylene blue must be administereddiscontinue SSRI immediately and monitor for CNS toxicitymay resume 24 hr after last linezolid or methylene blue doseor after 2 weeks of monitoring5 weeks for fluoxetinewhichever comes first.

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