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Cumulative urinary excretion of digoxin was comparable for both products and exceeded 40 of the administered dose by 24 hours.

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PO1st loading dose17.5-30 mcg/kg2nd and 3rd loading doses8.75-15 mcg/kg q6-8hr for 2 dosesmaintenance10-15 mcg/kg/day divided q12hr IV/IM1st loading dose15-25 mcg/kg2nd and 3rd loading doses7.5-12.5 mcg/kg q6-8hr for 2 dosesmaintenance7.5-12 mcg/kg/day divided q12hr.

You should not stop using digoxin suddenlyStopping suddenly may make your condition worse.

Generally avoid if left ventricular systolic function preservedalthough may be used for ventricular rate control in subgroup with chronic atrial fibrillation.

Erythromycin and tetracyclineantibioticsAntiarrhythmic drugsamiodaroneCalcium channel blockers Over-the-counter antacids Hawthornan herbal remedyBlack licorice Digoxin and black licorice can cause an irregular heartbeatLarge amounts of oatmealmilk and high-fibre cereals These can interfere with the absorption of digoxin.

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