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Kytril is primarily administered because it helps in reducing the activity of the pneumogastric nerve or vagus nerve, which is responsible for activating the vomiting center present in the lower half of the brainstem also known as medulla oblongata.

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Granisetron may cause a condition that affects the heart rhythmQT prolongationQT prolongation can rarely cause seriousrarely fatalfast/irregular heartbeat and other symptomssuch as severe dizzinessfaintingthat need medical attention right away.

There is no specific treatment for granisetron hydrochloride overdosageIn case of overdosagesymptomatic treatment should be givenOverdosage of up to 38.5 mg of granisetron hydrochloride injection has been reported without symptoms or only the occurrence of a slight headache.

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