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Use of cyclophosphamide during pregnancy may affect the fetusFetuses exposed to cyclophosphamide may be born with missing fingerstoes and a poorly-developed heartCyclophosphamide should not be administered during pregnancyCyclophosphamide is excreted in breast milk and could cause serious problems in the nursing infant.

5Dextrose InjectionUSP 5Dextrose and 0.9Sodium Chloride InjectionUSP 0.45Sodium Chloride InjectionUSP.

Metabolism and Nutritionhyponatremiafluid retentionblood glucose increasedblood glucose decreased.

Reconstitute Cyclophosphamide with 0.9Sodium Chloride InjectionUSP onlyusing the volumes listed below in Table 1Gently swirl the vial to dissolve the drug completelyDo not use Sterile Water for InjectionUSP because it results in a hypotonic solution and should not be injected directly.

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